GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Acts as a GTPase activitor in vitro for CDC42 and RAC1. sequence caution:Translation N-terminally extended. Contains 1 BAR domain. Contains 1 Rho-GAP domain. tissue specificity:Highly expressed in brain. Expressed at weak level in other tissues.
Immunogen
Synthesized peptide derived from human protein . at AA range: 430-510