catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquinated proteins. PTM:Phosphorylated upon DNA damage, probably by ATM or ATR. Belongs to the peptidase C19 family. tissue specificity:Expressed in brain at low level.
Immunogen
Synthesized peptide derived from part region of human protein