| Product description |
catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol. disease:Involved in tumorigenesis. Has an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. miscellaneous:The USP6 gene only exists in the primate lineage. Belongs to the peptidase C19 family. Contains 1 Rab-GAP TBC domain. tissue specificity:Testis specific. Expressed in various cancer cell lines. |