| Product Name | CCAR1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | May be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Plays a role in cell cycle progression and/or cell proliferation. PTM:Phosphorylated upon DNA damage, probably by ATM or ATR. sequence caution:Contaminating sequence. Potential poly-A sequence. Contains 1 SAP domain. tissue specificity:Expressed in various epithelial cancer cell lines, including breast, colon, prostate, pancreatic and leukemia. Expression is regulated by growth factors. |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 840-920 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Molecular Weight(MW) | 126 kDa |
|---|
| SwissProt ID | Q8IX12 |
|---|
| Positive Control | Epithelium,Hepatoma,Muscle,Placenta,Skin,Teratocarcinoma, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
