| Product Name | HUWE1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | This gene encodes a protein containing a C-terminal HECT (E6AP type E3 ubiquitin protein ligase) domain that functions as an E3 ubiquitin ligase. The encoded protein is required for the ubiquitination and subsequent degradation of the anti-apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2-related)). This protein also ubiquitinates the p53 tumor suppressor, core histones, and DNA polymerase beta. Mutations in this gene are associated with Turner type X-linked syndromic mental retardation. |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC |
| IHC:1:50-300 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Molecular Weight(MW) | 481 kDa |
|---|
| SwissProt ID | Q7Z6Z7 |
|---|
| Positive Control | Adipose tissue,Brain,Epithelium,Hum |
|---|---|
| Application Notes | IHC:1:50-300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
