May inhibit NODAL and BMP signaling during neural patterning (By similarity). May be a tumor suppressor in brain cancers. Belongs to the tomoregulin family. Belongs to the UPF0439 family. Contains 1 EGF-like domain. Contains 2 Kazal-like domains. subunit:May interact with ST14. tissue specificity:Expressed in brain. tissue specificity:Expressed predominantly in brain, and at lower levels in heart, placenta and skeletal muscle. Down-regulated in brain tumors as compared to control brain tissues.
Immunogen
Synthesized peptide derived from part region of human protein