| Product description |
May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression. induction:In monocytes, down-regulated by the cell-wall fraction of Mycobacterium bovis (BCG-CWS). subcellular location:Associated with CD180 at the cell surface. subunit:Binds CD180. tissue specificity:Highly expressed in B-cells, monocytes and tonsil. |