| Product Name | HBEGF |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts and smooth muscle but not endothelial cells. It is able to bind EGF receptors with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor. PTM:O-linked glycan attachment sites were determined by Edman degradation, O-glycanase digest suggests mucin-type glycosylation (done in HB-EGF purified from histiocytic lymphoma cell line U-937). PTM:Several N-termini have been identified by direct sequencing. The forms with N-termini 63, 73 and 74 have been tested and found to be biologically active. Contains 1 EGF-like domain. subcellular location:Mature HB-EGF is released into the extracellular space and probably binds to a receptor. |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 130-210 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanRatMouse |
| Concentration | 1mg/ml |
| Molecular Weight(MW) | 22 kDa |
|---|
| SwissProt ID | Q99075 |
|---|
| Positive Control | Brain,Eye,Histiocytic lymphoma,Macrophage, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
