| Product description |
May play a role in epithelial cell-cell contacts. May play a role in tumor invasiveness and metastasis formation. PTM:O-glycosylated. The O-glycan is modified with sialic acid residues. Belongs to the SMAGP family. subcellular location:Predominantly on lateral parts of the membrane, at cell-cell epithelial junctions. Detected on cytoplasmic membranes in undifferentiated tumors. tissue specificity:Detected in breast, endometrium, colon and biliary tract. Detected in polarized epithelial structures characterized by cell-cell adhesion (at protein level). |