| Product Name | LAX1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells. induction:Up-regulated in T-cells following TCR engagement. PTM:Phosphorylated on tyrosines by Syk, Lck or ZAP70 upon TCR or BCR activation; which leads to the recruitment of GRB2, PIK3R1 and GRAP2. subunit:When phosphorylated, interacts with GRB2, PIK3R1 and GRAP2. tissue specificity:Expressed in spleen, thymus, and peripheral blood leukocytes. Expressed in several B-, T-, NK and monocyte cell lines. |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 30-110 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanRatMouse |
| Concentration | 1mg/ml |
| Molecular Weight(MW) | 43 kDa |
|---|
| SwissProt ID | Q8IWV1 |
|---|
| Positive Control | Lymph, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
