May be involved in the regulation of p53-dependent G2 arrest of the cell cycle. Seems to induce cell cycle arrest by inhibiting CDC2 activity and nuclear translocation of the CDC2 cyclin B1 complex. induction:By TP53/p53, following X-ray irradiation. miscellaneous:'Reprimo' signifies stop/repress. Belongs to the reprimo family.
Immunogen
Synthesized peptide derived from part region of human protein