HSD3B7 antibody; 3 beta-hydroxysteroid dehydrogenase type 7 antibody; 3 beta-hydroxysteroid dehydrogenase type VII antibody; 3-beta-HSD VII antibody; 3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase antibody; C(27) 3-beta-HSD antibody; Cholest-5-ene-3-beta antibody; 7-alpha-diol 3-beta-dehydrogenase antibody;
Product description
This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen
The antiserum was produced against synthesized peptide derived from human HSD3B7. AA range:121-170
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB:1:500-1:2000
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Target Information
Alternative Names
HSD3B7 antibody 3 beta-hydroxysteroid dehydrogenase type 7 antibody 3 beta-hydroxysteroid dehydrogenase type VII antibody 3-beta-HSD VII antibody 3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase antibody C(27) 3-beta-HSD antibody Cholest-5-ene-3-beta antibody 7-alpha-diol 3-beta-dehydrogenase antibody