| Product Name | 4E-BP1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | EIF4EBP1 antibody; Eukaryotic translation initiation factor 4E-binding protein 1 antibody; 4E-BP1 antibody; eIF4E-binding protein 1 antibody; Phosphorylated heat- and acid-stable protein regulated by insulin 1 antibody; PHAS-I antibody; |
| Product description | EIF4EBP1 encodes one member (eukaryotic translation initiation factor 4E binding protein 1) of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. |
| Immunogen | The antiserum was produced against synthesized peptide derived from mouse 4E-BP1. AA range:35-84 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | MouseRatMonkey |
| Concentration | 1mg/ml |
| Alternative Names | EIF4EBP1 antibody Eukaryotic translation initiation factor 4E-binding protein 1 antibody 4E-BP1 antibody eIF4E-binding protein 1 antibody Phosphorylated heat- and acid-stable protein regulated by insulin 1 antibody PHAS-I antibody |
|---|---|
| Molecular Weight(MW) | 12 kDa |
| SwissProt ID | Q60876 |
|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
