| Product Name | AAK1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | AAK1 antibody; KIAA1048 antibody; AP2-associated protein kinase 1 antibody; Adaptor-associated kinase 1 antibody; |
| Product description | Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human AAK1. AA range:271-320 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | HumanMouseRatMonkey |
| Concentration | 1mg/ml |
| Alternative Names | AAK1 antibody KIAA1048 antibody AP2-associated protein kinase 1 antibody Adaptor-associated kinase 1 antibody |
|---|---|
| Molecular Weight(MW) | 94 kDa |
| SwissProt ID | Q2M2I8 |
|---|
| Positive Control | Brain,Cerebellum,Epithelium,Uterus, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
