| Product Name | ABHD12 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ABHD12 antibody; C20orf22 antibody; Monoacylglycerol lipase ABHD12 antibody; 2-arachidonoylglycerol hydrolase antibody; Abhydrolase domain-containing protein 12 antibody; |
| Product description | This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene., |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ABHD12. AA range:231-280 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | ABHD12 antibody C20orf22 antibody Monoacylglycerol lipase ABHD12 antibody 2-arachidonoylglycerol hydrolase antibody Abhydrolase domain-containing protein 12 antibody |
|---|---|
| Molecular Weight(MW) | 45 kDa |
| SwissProt ID | Q8N2K0 |
|---|
| Positive Control | Cerebellum,Kidney,Ovarian carcinoma,Pancreas,Testis, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
