| Product Name | Abi-1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ABI1 antibody; SSH3BP1 antibody; Abl interactor 1 antibody; Abelson interactor 1 antibody; Abi-1 antibody; Abl-binding protein 4 antibody; AblBP4 antibody; Eps8 SH3 domain-binding protein antibody; Eps8-binding protein antibody; Nap1-binding protein antibody; Nap1BP antibody; Spectrin SH3 domain-binding protein 1 antibody; e3B1 antibody; |
| Product description | This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10;11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14. [provided by RefSeq |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Abi-1. AA range:152-201 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | ABI1 antibody SSH3BP1 antibody Abl interactor 1 antibody Abelson interactor 1 antibody Abi-1 antibody Abl-binding protein 4 antibody AblBP4 antibody Eps8 SH3 domain-binding protein antibody Eps8-binding protein antibody Nap1-binding protein antibody Nap1BP antibody Spectrin SH3 domain-binding protein 1 antibody e3B1 antibody |
|---|---|
| Molecular Weight(MW) | 55 kDa |
| SwissProt ID | Q8IZP0 |
|---|
| Positive Control | Brain,Epithelium,Hepatoma,Muscle,Platelet,T-cell,Umbilical vein endothelial cell, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
