| Product Name | ACTR-IIA |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ACVR2A antibody; ACVR2 antibody; Activin receptor type-2A antibody; Activin receptor type IIA antibody; ACTR-IIA antibody; ACTRIIA antibody; |
| Product description | This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ACTR-IIA. AA range:10-59 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | ACVR2A antibody ACVR2 antibody Activin receptor type-2A antibody Activin receptor type IIA antibody ACTR-IIA antibody ACTRIIA antibody |
|---|---|
| Molecular Weight(MW) | 48 kDa |
| SwissProt ID | P27037 |
|---|
| Positive Control | Mammary gland,Testis, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
