| Product Name | Adducin α/β |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ADD1 antibody; ADDA antibody; Alpha-adducin antibody; Erythrocyte adducin subunit alpha antibody; ADD2 antibody; ADDB antibody; Beta-adducin antibody; Erythrocyte adducin subunit beta antibody; |
| Product description | Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ADD1. AA range:688-737 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCIPIF |
| WB:1:500-1:2000 IHC:1:100-1:300 Immunoprecipitation:2-5 ug/mg lysate IF:1:100-1:500 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | ADD1 antibody ADDA antibody Alpha-adducin antibody Erythrocyte adducin subunit alpha antibody ADD2 antibody ADDB antibody Beta-adducin antibody Erythrocyte adducin subunit beta antibody |
|---|---|
| Molecular Weight(MW) | 80 kDa |
| Positive Control | Brain cortex,Epithelium,Muscle,Platelet,Reticulocyte,Testis, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 Immunoprecipitation:2-5 ug/mg lysate IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
