| Product Name | AIP4 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ITCH antibody; E3 ubiquitin-protein ligase Itchy homolog antibody; Itch antibody; Atrophin-1-interacting protein 4 antibody; AIP4 antibody; NFE2-associated polypeptide 1 antibody; NAPP1 antibody; |
| Product description | This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ITCH. AA range:386-435 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | ITCH antibody E3 ubiquitin-protein ligase Itchy homolog antibody Itch antibody Atrophin-1-interacting protein 4 antibody AIP4 antibody NFE2-associated polypeptide 1 antibody NAPP1 antibody |
|---|---|
| Molecular Weight(MW) | 103 kDa |
| SwissProt ID | Q96J02 |
|---|
| Positive Control | Aorta endothelial cell,B-cell,Fetal brain,Kidney,Leukemia,Placenta,Trachea, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
