| Product Name | AKAP 13 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | AKAP13 antibody; BRX antibody; HT31 antibody; LBC antibody; A-kinase anchor protein 13 antibody; AKAP-13 antibody; AKAP-Lbc antibody; Breast cancer nuclear receptor-binding auxiliary protein antibody; Guanine nucleotide exchange factor Lbc antibody; Human thyroid-anchoring protein 31 antibody; Lymphoid blast crisis oncogene antibody; LBC antibody; |
| Product description | The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms containing c-terminal dbl oncogene homology (DH) and pleckstrin homology (PH) domains. The DH domain is associated with guanine nucleotide exchange activation for the Rho/Rac family of small GTP binding proteins, resulting in the conversion of the inactive GTPase to the active form capable of transducing signals. The PH domain has multiple functions. Therefore, these isoforms function as scaffolding proteins to coordinate a Rho signaling pathway, function as protein kinase A-anchoring proteins and, in addi |
| Immunogen | The antiserum was produced against synthesized peptide derived from human AKAP13. AA range:721-770 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | AKAP13 antibody BRX antibody HT31 antibody LBC antibody A-kinase anchor protein 13 antibody AKAP-13 antibody AKAP-Lbc antibody Breast cancer nuclear receptor-binding auxiliary protein antibody Guanine nucleotide exchange factor Lbc antibody Human thyroid-anchoring protein 31 antibody Lymphoid blast crisis oncogene antibody LBC antibody |
|---|---|
| Molecular Weight(MW) | 307 kDa |
| SwissProt ID | Q12802 |
|---|
| Positive Control | Brain,Epithelium,Lung,Skeletal muscle,Testis,Thyroid, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
