| Product Name | AKAP 79 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | AKAP5 antibody; AKAP79 antibody; A-kinase anchor protein 5 antibody; AKAP-5 antibody; A-kinase anchor protein 79 kDa antibody; AKAP 79 antibody; H21 antibody; cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein antibody; |
| Product description | The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human AKAP5. AA range:1-50 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | AKAP5 antibody AKAP79 antibody A-kinase anchor protein 5 antibody AKAP-5 antibody A-kinase anchor protein 79 kDa antibody AKAP 79 antibody H21 antibody cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein antibody |
|---|---|
| Molecular Weight(MW) | 47 kDa |
| SwissProt ID | P24588 |
|---|
| Positive Control | Kidney,PCR rescued clones,Pooled,Spleen,Thyroid, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
