This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene.
Immunogen
The antiserum was produced against synthesized peptide derived from human ALDH1A2. AA range:412-461
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHCWB
WB:1:500-1:2000 IHC:1:50-1:300
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
ALDH1A2 antibody RALDH2 antibody Retinal dehydrogenase 2 antibody RALDH 2 antibody RalDH2 antibody Aldehyde dehydrogenase family 1 member A2 antibody Retinaldehyde-specific dehydrogenase type 2 antibody RALDH(II) antibody