| Product Name | Apaf-1-ALT |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | APAF1-interacting protein antibody; APIP antibody; APIP2 antibody; CGI-29 protein antibody; MMRP19 antibody; dJ179L10.2 antibody; likely ortholog of mouse monocyte macrophage 19 antibody; |
| Product description | This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human APAF-1-ALT. AA range:289-338 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | APAF1-interacting protein antibody APIP antibody APIP2 antibody CGI-29 protein antibody MMRP19 antibody dJ179L10.2 antibody likely ortholog of mouse monocyte macrophage 19 antibody |
|---|---|
| Molecular Weight(MW) | 27 kDa |
| SwissProt ID | O14727 |
|---|
| Positive Control | Brain,Cervix carcinoma,Epithelium,Heart,Kidney,Peripheral blood,Pro |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
