| Product Name | APC5 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ANAPC5 antibody; APC5 antibody; Anaphase-promoting complex subunit 5 antibody; APC5 antibody; Cyclosome subunit 5 antibody; |
| Product description | This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ANAPC5. AA range:151-200 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | ANAPC5 antibody APC5 antibody Anaphase-promoting complex subunit 5 antibody APC5 antibody Cyclosome subunit 5 antibody |
|---|---|
| Molecular Weight(MW) | 85 kDa |
| SwissProt ID | Q9UJX4 |
|---|
| Positive Control | Brain,Cerebellum,Cervix,Epithelium,Lung,Oesophagus,Periodontal liga |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
