| Product Name | API5 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | API5 antibody; MIG8 antibody; Apoptosis inhibitor 5 antibody; API-5 antibody; Antiapoptosis clone 11 protein antibody; AAC-11 antibody; Cell migration-inducing gene 8 protein antibody; Fibroblast growth factor 2-interacting factor antibody; FIF antibody; Protein XAGL antibody; |
| Product description | This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human API-5. AA range:421-470 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | API5 antibody MIG8 antibody Apoptosis inhibitor 5 antibody API-5 antibody Antiapoptosis clone 11 protein antibody AAC-11 antibody Cell migration-inducing gene 8 protein antibody Fibroblast growth factor 2-interacting factor antibody FIF antibody Protein XAGL antibody |
|---|---|
| Molecular Weight(MW) | 58 kDa |
| SwissProt ID | Q9BZZ5 |
|---|
| Positive Control | Brain,Epithelium,Liver,Lymph,Ovarian carcinoma, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
