| Product Name | APLP-2 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | APLP2 antibody; APPL2 antibody; Amyloid-like protein 2 antibody; APLP-2 antibody; APPH antibody; Amyloid protein homolog antibody; CDEI box-binding protein antibody; CDEBP antibody; |
| Product description | This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human APLP2. AA range:241-290 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | APLP2 antibody APPL2 antibody Amyloid-like protein 2 antibody APLP-2 antibody APPH antibody Amyloid protein homolog antibody CDEI box-binding protein antibody CDEBP antibody |
|---|---|
| Molecular Weight(MW) | 87 kDa |
| SwissProt ID | Q06481 |
|---|
| Positive Control | Brain,Lung,Ovary,Pancreas,Placenta,Testis,Uterus, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
