SH2B2 antibody; APS antibody; SH2B adapter protein 2 antibody; Adapter protein with pleckstrin homology and Src homology 2 domains antibody; SH2 and PH domain-containing adapter protein APS antibody;
Product description
The protein encoded by this gene is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine-phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc/Grb2 pathway.
Immunogen
Synthesized peptide derived from the Internal region of human APS.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB:1:500-1:2000
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Target Information
Alternative Names
SH2B2 antibody APS antibody SH2B adapter protein 2 antibody Adapter protein with pleckstrin homology and Src homology 2 domains antibody SH2 and PH domain-containing adapter protein APS antibody