| Product Name | AR α2C |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ADRA2C antibody; ADRA2L2 antibody; ADRA2RL2 antibody; Alpha-2C adrenergic receptor antibody; Alpha-2 adrenergic receptor subtype C4 antibody; Alpha-2C adrenoreceptor antibody; Alpha-2C adrenoceptor antibody; Alpha-2CAR antibody; |
| Product description | Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Adrenergic Receptor alpha-2C. AA range:336-385 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | ADRA2C antibody ADRA2L2 antibody ADRA2RL2 antibody Alpha-2C adrenergic receptor antibody Alpha-2 adrenergic receptor subtype C4 antibody Alpha-2C adrenoreceptor antibody Alpha-2C adrenoceptor antibody Alpha-2CAR antibody |
|---|---|
| Molecular Weight(MW) | 70 kDa |
| SwissProt ID | P18825 |
|---|
| Positive Control | Brain,Donated clones,Kidney, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
