RNF14 antibody; ARA54 antibody; HRIHFB2038 antibody; E3 ubiquitin-protein ligase RNF14 antibody; Androgen receptor-associated protein 54 antibody; HFB30 antibody; RING finger protein 14 antibody; Triad2 protein antibody;
Product description
The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Six alternatively spliced transcript variants encoding two distinct isoforms have been reported.
Immunogen
The antiserum was produced against synthesized peptide derived from human RNF14. AA range:361-410
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB:1:500-1:2000
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Target Information
Alternative Names
RNF14 antibody ARA54 antibody HRIHFB2038 antibody E3 ubiquitin-protein ligase RNF14 antibody Androgen receptor-associated protein 54 antibody HFB30 antibody RING finger protein 14 antibody Triad2 protein antibody