| Product Name | ASC-1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TRIP4 antibody; Activating signal cointegrator 1 antibody; ASC-1 antibody; Thyroid receptor-interacting protein 4 antibody; TR-interacting protein 4 antibody; TRIP-4 antibody; |
| Product description | This gene encodes a subunit of the tetrameric nuclear activating signal cointegrator 1 (ASC-1) complex, which associates with transcriptional coactivators, nuclear receptors and basal transcription factors to facilitate nuclear receptors-mediated transcription. This protein is localized in the nucleus and contains an E1A-type zinc finger domain, which mediates interaction with transcriptional coactivators and ligand-bound nuclear receptors, such as thyroid hormone receptor and retinoid X receptor alpha, but not glucocorticoid receptor. Mutations in this gene are associated with spinal muscular atrophy with congenital bone fractures-1 (SMABF1). |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TRIP4. AA range:81-130 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | TRIP4 antibody Activating signal cointegrator 1 antibody ASC-1 antibody Thyroid receptor-interacting protein 4 antibody TR-interacting protein 4 antibody TRIP-4 antibody |
|---|---|
| Molecular Weight(MW) | 66 kDa |
| SwissProt ID | Q15650 |
|---|
| Positive Control | Lung, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
