| Product Name | ATP7A |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ATP7A antibody; MC1 antibody; MNK antibody; Copper-transporting ATPase 1 antibody; Copper pump 1 antibody; Menkes disease-associated protein antibody; |
| Product description | This gene encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. It relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in this gene are associated with Menkes disease, X-linked distal spinal muscular atrophy, and occipital horn syndrome. Alternatively-spliced transcript variants have been observed. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ATP7A. AA range:591-640 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC |
| IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | ATP7A antibody MC1 antibody MNK antibody Copper-transporting ATPase 1 antibody Copper pump 1 antibody Menkes disease-associated protein antibody |
|---|---|
| Molecular Weight(MW) | kDa |
| SwissProt ID | Q04656 |
|---|
| Positive Control | Brain,Colon carcinoma,Endothelial cell,Fibroblast,Kidney,Neuroblastoma, |
|---|---|
| Application Notes | IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
