| Product Name | ATP7B |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ATP7B antibody; PWD antibody; WC1 antibody; WND antibody; Copper-transporting ATPase 2 antibody; Copper pump 2 antibody; Wilson disease-associated protein antibody; |
| Product description | This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD). |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ATP7B. AA range:161-210 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCIF |
| IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | ATP7B antibody PWD antibody WC1 antibody WND antibody Copper-transporting ATPase 2 antibody Copper pump 2 antibody Wilson disease-associated protein antibody |
|---|---|
| Molecular Weight(MW) | kDa |
| SwissProt ID | P35670 |
|---|
| Positive Control | Brain,Liver,Pooled, |
|---|---|
| Application Notes | IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
