| Product Name | Atrophin-1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ATN1 antibody; D12S755E antibody; DRPLA antibody; Atrophin-1 antibody; Dentatorubral-pallidoluysian atrophy protein antibody; |
| Product description | Dentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion from 7-35 copies to 49-93 copies of a trinucleotide repeat (CAG/CAA) within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human ATN1. AA range:81-130 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | ATN1 antibody D12S755E antibody DRPLA antibody Atrophin-1 antibody Dentatorubral-pallidoluysian atrophy protein antibody |
|---|---|
| Molecular Weight(MW) | 130 kDa |
| SwissProt ID | P54259 |
|---|
| Positive Control | Brain,Brain cortex,Cerebellum,Epithelium, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
