| Product Name | Bcl-w |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | BCL2L2 antibody; BCLW antibody; KIAA0271 antibody; Bcl-2-like protein 2 antibody; Bcl2-L-2 antibody; Apoptosis regulator Bcl-W antibody; |
| Product description | This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human BCLW. AA range:131-180 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | BCL2L2 antibody BCLW antibody KIAA0271 antibody Bcl-2-like protein 2 antibody Bcl2-L-2 antibody Apoptosis regulator Bcl-W antibody |
|---|---|
| Molecular Weight(MW) | 25 kDa |
| SwissProt ID | Q92843 |
|---|
| Positive Control | Brain,Lung, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
