| Product Name |
BMP-8B |
| Antibody Type |
Primary Antibodies |
| Antigen Alias |
BMP8B antibody; BMP8 antibody; Bone morphogenetic protein 8B antibody; BMP-8 antibody; BMP-8B antibody; Osteogenic protein 2 antibody; OP-2 antibody; |
| Product description |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of this gene may be downregulated in pancreatic cancer. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1. |
| Immunogen |
The antiserum was produced against synthesized peptide derived from human BMP8B. AA range:261-310 |