| Product Name | BRSK1 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | BRSK1 antibody; KIAA1811 antibody; SAD1 antibody; SADB antibody; Serine/threonine-protein kinase BRSK1 antibody; Brain-selective kinase 1 antibody; Brain-specific serine/threonine-protein kinase 1 antibody; BR serine/threonine-protein kinase 1 antibody; Serine/threonine-protein kinase SAD-B antibody; Synapses of Amphids antibody; |
| Product description | catalytic activity:ATP + a protein = ADP + a phosphoprotein. cofactor:Magnesium. enzyme regulation:Activated by phosphorylation on Thr-205 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39. Required for the polarization of forebrain neurons which endows axons and dendrites with distinct properties, possibly by locally regulating phosphorylation of microtubule-associated proteins (By similarity). May be involved in the regulation of G2/M arrest in response to UV- or methyl methane sulfonate (MMS)-induced, but not IR-induced, DNA damage. Phosphorylates WEE1 and CDC25B in vitro and CDC25C in vitro and in vivo. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. AMPK subfamily. Contains 1 protein kinase domain. Contains 1 UBA domain. subcellular location:Nuclear in the absence of DNA damage. Translocated to the nucleus in response to UV- or MMS-induced DNA damage. tissue specificity:Widely expressed, with highest levels in brain and testis. Protein levels remain constant throughout the cell cycle. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human BRSK1. AA range:361-410 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIF |
| WB:1:500-1:2000 IF:1:100-1:500 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | BRSK1 antibody KIAA1811 antibody SAD1 antibody SADB antibody Serine/threonine-protein kinase BRSK1 antibody Brain-selective kinase 1 antibody Brain-specific serine/threonine-protein kinase 1 antibody BR serine/threonine-protein kinase 1 antibody Serine/threonine-protein kinase SAD-B antibody Synapses of Amphids antibody |
|---|---|
| Molecular Weight(MW) | 87 kDa |
| SwissProt ID | Q8TDC3 |
|---|
| Positive Control | Brain,Lymph,Testis, |
|---|---|
| Application Notes | WB:1:500-1:2000 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
