| Product Name | CA VIII |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CA8 antibody; CALS antibody; Carbonic anhydrase-related protein antibody; CARP antibody; Carbonic anhydrase VIII antibody; CA-VIII antibody; |
| Product description | The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i. e. the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form. Mutations in this gene are associated with cerebellar ataxia, mental retardation, and dysequilibrium syndrome 3 (CMARQ3). Polymorphisms in this gene are associated with osteoporosis, and overexpression of this gene in osteosarcoma cells suggests an oncogenic role. Alternative splicing results in multiple transcript variants. [provid |
| Immunogen | Synthesized peptide derived from the Internal region of human CA VIII. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC |
| IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | CA8 antibody CALS antibody Carbonic anhydrase-related protein antibody CARP antibody Carbonic anhydrase VIII antibody CA-VIII antibody |
|---|---|
| Molecular Weight(MW) | kDa |
| SwissProt ID | P35219 |
|---|
| Application Notes | IHC:1:100-1:300 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
