| Product Name | Calpain 10 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CAPN10 antibody; KIAA1845 antibody; Calpain-10 antibody; Calcium-activated neutral proteinase 10 antibody; CANP 10 antibody; |
| Product description | Calpains represent a ubiquitous, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation; domain II, the protease domain; domain III, a linker domain of unknown function; and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM), and is located within the NIDDM1 region. Multiple alternative transcript variants have been described for this gene. [provided by RefSeq, |
| Immunogen | Synthesized peptide derived from the N-terminal region of human Calpain 10. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CAPN10 antibody KIAA1845 antibody Calpain-10 antibody Calcium-activated neutral proteinase 10 antibody CANP 10 antibody |
|---|---|
| Molecular Weight(MW) | 75 kDa |
| SwissProt ID | Q9HC96 |
|---|
| Positive Control | Brain,Skin,Uterus, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
