| Product Name | CARD 11 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CARD11 antibody; CARMA1 antibody; Caspase recruitment domain-containing protein 11 antibody; CARD-containing MAGUK protein 1 antibody; Carma 1 antibody; |
| Product description | The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CARD11. AA range:10-59 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | CARD11 antibody CARMA1 antibody Caspase recruitment domain-containing protein 11 antibody CARD-containing MAGUK protein 1 antibody Carma 1 antibody |
|---|---|
| Molecular Weight(MW) | 130 kDa |
| SwissProt ID | Q9BXL7 |
|---|
| Positive Control | Spleen, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
