| Product Name | Caspase-10 B/C |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ALPS2 antibody; apoptotic protease Mch-4 antibody; CASP-10 antibody; CASPA antibody; caspase-10 antibody; FADD-like ICE2 antibody; FAS-associated death domain protein interleukin-1B-convert antibody; |
| Product description | This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Caspase 10. AA range:430-479 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | ALPS2 antibody apoptotic protease Mch-4 antibody CASP-10 antibody CASPA antibody caspase-10 antibody FADD-like ICE2 antibody FAS-associated death domain protein interleukin-1B-convert antibody |
|---|---|
| Molecular Weight(MW) | 60 kDa |
| SwissProt ID | Q92851 |
|---|
| Positive Control | Blood,Brain,Spleen,T-cell,Thymus, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
