| Product Name | CaSR |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CASR antibody; GPRC2A antibody; PCAR1 antibody; Extracellular calcium-sensing receptor antibody; CaSR antibody; Parathyroid cell calcium-sensing receptor antibody; PCaR1 antibody; |
| Product description | The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Calcium Sensing Receptor. AA range:854-903 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | CASR antibody GPRC2A antibody PCAR1 antibody Extracellular calcium-sensing receptor antibody CaSR antibody Parathyroid cell calcium-sensing receptor antibody PCaR1 antibody |
|---|---|
| Molecular Weight(MW) | 140 kDa |
| SwissProt ID | P41180 |
|---|
| Positive Control | Brain,Kidney,Parathyroid, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
