| Product Name | CD30-L |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TNFSF8 antibody; CD30L antibody; CD30LG antibody; Tumor necrosis factor ligand superfamily member 8 antibody; CD30 ligand antibody; CD30-L antibody; CD antigen CD153 antibody; |
| Product description | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CD153. AA range:71-120 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIF |
| WB:1:500-1:2000 IF:1:100-1:500 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | TNFSF8 antibody CD30L antibody CD30LG antibody Tumor necrosis factor ligand superfamily member 8 antibody CD30 ligand antibody CD30-L antibody CD antigen CD153 antibody |
|---|---|
| Molecular Weight(MW) | 38 kDa |
| SwissProt ID | P32971 |
|---|
| Positive Control | Brain,Thymus, |
|---|---|
| Application Notes | WB:1:500-1:2000 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
