| Product Name | CD314 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | KLRK1 antibody; D12S2489E antibody; NKG2D antibody; NKG2-D type II integral membrane protein antibody; Killer cell lectin-like receptor subfamily K member 1 antibody; NK cell receptor D antibody; NKG2-D-activating NK receptor antibody; CD antigen CD314 antibody; |
| Product description | Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. This gene encodes a member of the NKG2 family. The encoded transmembrane protein is characterized by a type II membrane orientation (has an extracellular C terminus) and the presence of a C-type lectin domain. It binds to a diverse family of ligands that include MHC class I chain-related A and B proteins and UL-16 binding proteins, where ligand-receptor interactions can result in the activation of |
| Immunogen | The antiserum was produced against synthesized peptide derived from human KLRK1. AA range:111-160 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | KLRK1 antibody D12S2489E antibody NKG2D antibody NKG2-D type II integral membrane protein antibody Killer cell lectin-like receptor subfamily K member 1 antibody NK cell receptor D antibody NKG2-D-activating NK receptor antibody CD antigen CD314 antibody |
|---|---|
| Molecular Weight(MW) | 25 kDa |
| SwissProt ID | P26718 |
|---|
| Positive Control | Spleen,Stomach,Testis, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
