| Product Name | Cdc42EP5 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CDC42EP5 antibody; BORG3 antibody; CEP5 antibody; Cdc42 effector protein 5 antibody; Binder of Rho GTPases 3 antibody; |
| Product description | Cell division control protein 42 (CDC42), a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg (binder of Rho GTPases) family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to CDC42 and regulate its function negatively. The encoded protein may inhibit c-Jun N-terminal kinase (JNK) independently of CDC42 binding. The protein may also play a role in septin organization and inducing pseudopodia formation in fibroblasts |
| Immunogen | The antiserum was produced against synthesized peptide derived from human BORG3. AA range:1-50 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Alternative Names | CDC42EP5 antibody BORG3 antibody CEP5 antibody Cdc42 effector protein 5 antibody Binder of Rho GTPases 3 antibody |
|---|---|
| Molecular Weight(MW) | 22 kDa |
| SwissProt ID | Q6NZY7 |
|---|
| Positive Control | Bone,Pancreas, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
