CDCA3 antibody; C8 antibody; GRCC8 antibody; TOME1 antibody; Cell division cycle-associated protein 3 antibody; Gene-rich cluster protein C8 antibody; Trigger of mitotic entry protein 1 antibody; TOME-1 antibody;
Product description
domain:The KEN box is required for the association with the APC/C-Cdh1 complex. F-box-like protein which is required for entry into mitosis. Acts by participating to E3 ligase complexes that mediate the ubiquitination and degradation of WEE1 kinase at G2/M phase. pathway:Protein modification; protein ubiquitination. PTM:Phosphorylated upon DNA damage, probably by ATM or ATR. PTM:Ubiquitinated and degraded by the APC/C-Cdh1 complex. subunit:Interacts with SKP1A. Part of a SCF (SKP1-cullin-F-box) protein ligase complex.
Immunogen
The antiserum was produced against synthesized peptide derived from human CDCA3. AA range:219-268
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIHCIF
WB:1:500-1:2000 IHC:1:100-1:300 IF:1:100-1:500
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Target Information
Alternative Names
CDCA3 antibody C8 antibody GRCC8 antibody TOME1 antibody Cell division cycle-associated protein 3 antibody Gene-rich cluster protein C8 antibody Trigger of mitotic entry protein 1 antibody TOME-1 antibody