| Product Name | CENP-A |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CENPA antibody; Histone H3-like centromeric protein A antibody; Centromere autoantigen A antibody; Centromere protein A antibody; CENP-A antibody; |
| Product description | Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. This gene encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. Centromere protein A is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. The protein is a replication-independent histone that is a member of the histone H3 family. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Centromeric Protein A. AA range:1-50 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHCIF |
| IHC:1:100-1:300 IF:1:100-1:500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CENPA antibody Histone H3-like centromeric protein A antibody Centromere autoantigen A antibody Centromere protein A antibody CENP-A antibody |
|---|---|
| Molecular Weight(MW) | kDa |
| SwissProt ID | P49450 |
|---|
| Positive Control | Epithelium,Uterus, |
|---|---|
| Application Notes | IHC:1:100-1:300 IF:1:100-1:500 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
