| Product Name | CEP57 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CEP57 antibody; KIAA0092 antibody; TSP57 antibody; Centrosomal protein of 57 kDa antibody; Cep57 antibody; FGF2-interacting protein antibody; Testis-specific protein 57 antibody; Translokin antibody; |
| Product description | This gene encodes a cytoplasmic protein called Translokin. This protein localizes to the centrosome and has a function in microtubular stabilization. The N-terminal half of this protein is required for its centrosome localization and for its multimerization, and the C-terminal half is required for nucleating, bundling and anchoring microtubules to the centrosomes. This protein specifically interacts with fibroblast growth factor 2 (FGF2), sorting nexin 6, Ran-binding protein M and the kinesins KIF3A and KIF3B, and thus mediates the nuclear translocation and mitogenic activity of the FGF2. It also interacts with cyclin D1 and controls nucleocytoplasmic distribution of the cyclin D1 in quiescent cells. This protein is crucial for maintaining correct chromosomal number during cell division. Mutations in this gene cause mosaic variegated aneuploidy syndrome, a rare autosomal recessive disorder. Multiple |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CEP57. AA range:241-290 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500-1:2000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CEP57 antibody KIAA0092 antibody TSP57 antibody Centrosomal protein of 57 kDa antibody Cep57 antibody FGF2-interacting protein antibody Testis-specific protein 57 antibody Translokin antibody |
|---|---|
| Molecular Weight(MW) | 50 kDa |
| SwissProt ID | Q86XR8 |
|---|
| Positive Control | Bone marrow,Mammary gland,Placenta, |
|---|---|
| Application Notes | WB:1:500-1:2000 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
