| Product Name | c-Fgr |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FGR antibody; SRC2 antibody; Tyrosine-protein kinase Fgr antibody; Gardner-Rasheed feline sarcoma viral antibody; v-fgr) oncogene homolog antibody; Proto-oncogene c-Fgr antibody; p55-Fgr antibody; p58-Fgr antibody; p58c-Fgr antibody; |
| Product description | This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human FGR. AA range:61-110 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500-1:2000 IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | FGR antibody SRC2 antibody Tyrosine-protein kinase Fgr antibody Gardner-Rasheed feline sarcoma viral antibody v-fgr) oncogene homolog antibody Proto-oncogene c-Fgr antibody p55-Fgr antibody p58-Fgr antibody p58c-Fgr antibody |
|---|---|
| Molecular Weight(MW) | 55 kDa |
| SwissProt ID | P09769 |
|---|
| Positive Control | Brain, |
|---|---|
| Application Notes | WB:1:500-1:2000 IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
