CHP2 antibody; HCA520 antibody; Calcineurin B homologous protein 2 antibody; Hepatocellular carcinoma-associated antigen 520 antibody;
Product description
This gene product is a small calcium-binding protein that regulates cell pH by controlling plasma membrane-type Na+/H+ exchange activity. This protein shares sequence similarity with calcineurin B and can bind to and stimulate the protein phosphatase activity of calcineurin A (CnA) and functions in the calcineurin/NFAT (nuclear factor of activated T cells) signaling pathway. Another member of the CHP subfamily, Calcineurin B homologous protein 1, is located on Chromosome 15 and is an inhibitor of calcineurin activity and has a genetic phenotype associated with Parkinson's Disease (OMIM:606988). This gene was initially identified as a tumor-associated antigen and was previously referred to as Hepatocellular carcinoma-associated antigen 520.
Immunogen
The antiserum was produced against synthesized peptide derived from human CHP2. AA range:101-150
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB:1:500-1:2000
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Target Information
Alternative Names
CHP2 antibody HCA520 antibody Calcineurin B homologous protein 2 antibody Hepatocellular carcinoma-associated antigen 520 antibody