| Product Name | CKR-5 |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CCR5 antibody; CMKBR5 antibody; C-C chemokine receptor type 5 antibody; C-C CKR-5 antibody; CC-CKR-5 antibody; CCR-5 antibody; CCR5 antibody; CHEMR13 antibody; HIV-1 fusion coreceptor antibody; CD antigen CD195 antibody; |
| Product description | This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemok |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CCR5. AA range:292-341 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC |
| IHC:1:100-1:300 |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Alternative Names | CCR5 antibody CMKBR5 antibody C-C chemokine receptor type 5 antibody C-C CKR-5 antibody CC-CKR-5 antibody CCR-5 antibody CCR5 antibody CHEMR13 antibody HIV-1 fusion coreceptor antibody CD antigen CD195 antibody |
|---|---|
| Molecular Weight(MW) | 41 kDa |
| SwissProt ID | P51681 |
|---|
| Positive Control | Macrophage,PBMC,Synovial membrane tissue, |
|---|---|
| Application Notes | IHC:1:100-1:300 |
| Form | Liquid |
|---|---|
| Storage Instructions | Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles. |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
